Fentanyl (Buccal mucosa, Oromucosal, Sublingual)

["Before using fentanyl", "In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do This is a decision you and your doctor will make For this medicine, the following should be considered:", "Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals For non-prescription products, read the label or package ingredients carefully.", "Appropriate studies have not been performed on the relationship of age to the effects of fentanyl in children younger than 18 years of age for the Abstral\\\\u00ae, Fentora\\\\u00ae, Onsolis\\\\u00ae, and Subsys\\\\u00ae brands, and in children younger than 16 years of age for the Actiq\\\\u00ae brand Safety and efficacy have not been established in these age groups. ", "Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fentanyl in the elderly However, elderly patients may be more sensitive to the effects of narcotic analgesics than younger adults and are more likely to have age-related lung or kidney problems, which may require caution and an adjustment in the dose for patients receiving fentanyl in order to avoid serious side effects. ", "There are no adequate studies in women for determining infant risk when using this medication during breastfeeding Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.", "Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur In these cases, your doctor may want to change the dose, or other precautions may be necessary When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.", "Using this medicine with any of the following medicines is not recommended Your doctor may decide not to treat you with this medication or change some of the other medicines you take.", "Levoketoconazole\\\\nMifepristone\\\\nNalmefene\\\\nNaltrexone\\\\nSafinamide\\\\nSamidorphan", "Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.", "Abametapir\\\\nAcepromazine\\\\nAdagrasib\\\\nAlefacept\\\\nAlfentanil\\\\nAlmotriptan\\\\nAlprazolam\\\\nAmifampridine\\\\nAmineptine\\\\nAmiodarone\\\\nAmitriptyline\\\\nAmitriptylinoxide\\\\nAmobarbital\\\\nAmoxapine\\\\nAmphetamine\\\\nAmprenavir\\\\nAnileridine\\\\nAprepitant\\\\nAripiprazole\\\\nArmodafinil\\\\nAsciminib\\\\nAsenapine\\\\nAtazanavir\\\\nAvacopan\\\\nBaclofen\\\\nBelzutifan\\\\nBenperidol\\\\nBenzhydrocodone\\\\nBenzphetamine\\\\nBerotralstat\\\\nBoceprevir\\\\nBosentan\\\\nBromazepam\\\\nBromopride\\\\nBrompheniramine\\\\nBuprenorphine\\\\nBupropion\\\\nBuspirone\\\\nButabarbital\\\\nButorphanol\\\\nCalcium Oxybate\\\\nCannabidiol\\\\nCannabis\\\\nCarbamazepine\\\\nCarbinoxamine\\\\nCariprazine\\\\nCarisoprodol\\\\nCarphenazine\\\\nCeritinib\\\\nCetirizine\\\\nChloral Hydrate\\\\nChlordiazepoxide\\\\nChlorpheniramine\\\\nChlorpromazine\\\\nChlorzoxazone\\\\nCiprofloxacin\\\\nCitalopram\\\\nClarithromycin\\\\nClobazam\\\\nClomipramine\\\\nClonazepam\\\\nClopidogrel\\\\nClorazepate\\\\nClozapine\\\\nCobicistat\\\\nCocaine\\\\nCodeine\\\\nConivaptan\\\\nCrizotinib\\\\nCyclobenzaprine\\\\nCyclosporine\\\\nDabrafenib\\\\nDaridorexant\\\\nDarunavir\\\\nDelavirdine\\\\nDesipramine\\\\nDesmopressin\\\\nDesvenlafaxine\\\\nDexamethasone\\\\nDexmedetomidine\\\\nDextroamphetamine\\\\nDextromethorphan\\\\nDezocine\\\\nDiazepam\\\\nDibenzepin\\\\nDichloralphenazone\\\\nDifenoxin\\\\nDihydrocodeine\\\\nDiltiazem\\\\nDiphenhydramine\\\\nDiphenoxylate\\\\nDolasetron\\\\nDonepezil\\\\nDoxepin\\\\nDronedarone\\\\nDroperidol\\\\nDuloxetine\\\\nEfavirenz\\\\nEletriptan\\\\nEluxadoline\\\\nEnflurane\\\\nEnzalutamide\\\\nErdafitinib\\\\nErythromycin\\\\nEscitalopram\\\\nEsketamine\\\\nEslicarbazepine Acetate\\\\nEstazolam\\\\nEszopiclone\\\\nEthchlorvynol\\\\nEthopropazine\\\\nEthylmorphine\\\\nEtravirine\\\\nFedratinib\\\\nFenfluramine\\\\nFexinidazole\\\\nFlibanserin\\\\nFluconazole\\\\nFluoxetine\\\\nFluphenazine\\\\nFlurazepam\\\\nFluspirilene\\\\nFluvoxamine\\\\nFosamprenavir\\\\nFosaprepitant\\\\nFosnetupitant\\\\nFosphenytoin\\\\nFospropofol\\\\nFrovatriptan\\\\nFurazolidone\\\\nGabapentin\\\\nGabapentin Enacarbil\\\\nGepirone\\\\nGranisetron\\\\nHalazepam\\\\nHaloperidol\\\\nHalothane\\\\nHexobarbital\\\\nHydrocodone\\\\nHydromorphone\\\\nHydroxyamphetamine\\\\nHydroxytryptophan\\\\nHydroxyzine\\\\nIdelalisib\\\\nImatinib\\\\nImipramine\\\\nIndinavir\\\\nIproniazid\\\\nIsocarboxazid\\\\nIsoflurane\\\\nItraconazole\\\\nIvacaftor\\\\nKetamine\\\\nKetobemidone\\\\nKetoconazole\\\\nLacosamide\\\\nLanreotide\\\\nLasmiditan\\\\nLefamulin\\\\nLemborexant\\\\nLenacapavir\\\\nLevocetirizine\\\\nLevomilnacipran\\\\nLevorphanol\\\\nLinezolid\\\\nLisdexamfetamine\\\\nLithium\\\\nLofepramine\\\\nLofexidine\\\\nLomitapide\\\\nLopinavir\\\\nLorazepam\\\\nLorcaserin\\\\nLorlatinib\\\\nLoxapine\\\\nLumacaftor\\\\nMagnesium Oxybate\\\\nMavacamten\\\\nMeclizine\\\\nMelitracen\\\\nMelperone\\\\nMeperidine\\\\nMephobarbital\\\\nMeprobamate\\\\nMeptazinol\\\\nMesoridazine\\\\nMetaxalone\\\\nMethadone\\\\nMethamphetamine\\\\nMethdilazine\\\\nMethocarbamol\\\\nMethohexital\\\\nMethotrimeprazine\\\\nMethylene Blue\\\\nMetoclopramide\\\\nMibefradil\\\\nMidazolam\\\\nMilnacipran\\\\nMirtazapine\\\\nMitotane\\\\nMobocertinib\\\\nMoclobemide\\\\nModafinil\\\\nMolindone\\\\nMoricizine\\\\nMorphine\\\\nMorphine Sulfate Liposome\\\\nNafcillin\\\\nNalbuphine\\\\nNaratriptan\\\\nNefazodone\\\\nNelfinavir\\\\nNetupitant\\\\nNevirapine\\\\nNialamide\\\\nNicardipine\\\\nNicomorphine\\\\nNifedipine\\\\nNilotinib\\\\nNirmatrelvir\\\\nNitrazepam\\\\nNitrous Oxide\\\\nNortriptyline\\\\nOctreotide\\\\nOlanzapine\\\\nOmaveloxolone\\\\nOndansetron\\\\nOpipramol\\\\nOpium\\\\nOpium Alkaloids\\\\nOrphenadrine\\\\nOxazepam\\\\nOxcarbazepine\\\\nOxycodone\\\\nOxymorphone\\\\nOzanimod\\\\nPalbociclib\\\\nPalonosetron\\\\nPapaveretum\\\\nParegoric\\\\nParoxetine\\\\nPazopanib\\\\nPentazocine\\\\nPentobarbital\\\\nPerampanel\\\\nPerazine\\\\nPericiazine\\\\nPerphenazine\\\\nPhenelzine\\\\nPhenobarbital\\\\nPhenytoin\\\\nPimozide\\\\nPiperacetazine\\\\nPipotiazine\\\\nPiritramide\\\\nPirtobrutinib\\\\nPosaconazole\\\\nPotassium Oxybate\\\\nPrazepam\\\\nPrednisone\\\\nPregabalin\\\\nPrimidone\\\\nProcarbazine\\\\nProchlorperazine\\\\nPromazine\\\\nPromethazine\\\\nPropofol\\\\nProtriptyline\\\\nQuazepam\\\\nQuetiapine\\\\nRamelteon\\\\nRanitidine\\\\nRanolazine\\\\nRasagiline\\\\nRemifentanil\\\\nRemimazolam\\\\nRemoxipride\\\\nRibociclib\\\\nRifabutin\\\\nRifampin\\\\nRifapentine\\\\nRitlecitinib\\\\nRitonavir\\\\nRizatriptan\\\\nRopeginterferon Alfa-2b-njft\\\\nSaquinavir\\\\nScopolamine\\\\nSecobarbital\\\\nSelegiline\\\\nSelpercatinib\\\\nSertindole\\\\nSertraline\\\\nSibutramine\\\\nSodium Oxybate\\\\nSotorasib\\\\nSt John's Wort\\\\nSufentanil\\\\nSulpiride\\\\nSumatriptan\\\\nSuvorexant\\\\nTacrolimus\\\\nTapentadol\\\\nTaurursodiol\\\\nTelaprevir\\\\nTelithromycin\\\\nTemazepam\\\\nThiethylperazine\\\\nThiopental\\\\nThiopropazate\\\\nThioridazine\\\\nTianeptine\\\\nTilidine\\\\nTizanidine\\\\nTocilizumab\\\\nTolonium Chloride\\\\nTopiramate\\\\nTramadol\\\\nTranylcypromine\\\\nTrazodone\\\\nTriazolam\\\\nTrifluoperazine\\\\nTrifluperidol\\\\nTriflupromazine\\\\nTrimeprazine\\\\nTrimipramine\\\\nTrofinetide\\\\nTryptophan\\\\nTucatinib\\\\nVenlafaxine\\\\nVerapamil\\\\nVilazodone\\\\nVoriconazole\\\\nVortioxetine\\\\nVoxelotor\\\\nZaleplon\\\\nZiprasidone\\\\nZolmitriptan\\\\nZolpidem\\\\nZopiclone\\\\nZotepine\\\\nZuranolone", "Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur Using alcohol or tobacco with certain medicines may also cause interactions to occur The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.", "Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.", "Ethanol\\\\nGrapefruit Juice", "The presence of other medical problems may affect the use of this medicine Make sure you tell your doctor if you have any other medical problems, especially:", "Alcohol abuse, or history of or\\\\nBrain tumor, history of or\\\\nBreathing problems (eg, asthma, apnea) or\\\\nChronic obstructive pulmonary disease (COPD) or\\\\nCor pulmonale (serious heart condition) or\\\\nDepression, history of or\\\\nDrug dependence, especially narcotic abuse, history of or\\\\nHead injury, history of or\\\\nMental health problems, history of\\\\u2014Use with caution May cause side effects to become worse. ", "Bradyarrhythmia (slow heart rhythm) or\\\\nHypotension (low blood pressure) or\\\\nPancreatitis (inflammation of the pancreas)\\\\u2014Use with caution May make these conditions worse. ", "Diabetes\\\\u2014Use the Actiq\\\\u00ae brand with caution There are 2 grams of sugar in each unit. ", "Kidney disease or\\\\nLiver disease\\\\u2014Use with caution The effects may be increased because of slower removal of the medicine from the body. ", "Stomach or bowel blockage (including paralytic ileus), known or suspected\\\\u2014Should not be used in patients with these conditions. "]