Melphalan (Intra-arterial, Intravenous)

["Before using melphalan", "In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do This is a decision you and your doctor will make For this medicine, the following should be considered:", "Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals For non-prescription products, read the label or package ingredients carefully.", "Appropriate studies have not been performed on the relationship of age to the effects of melphalan injection in the pediatric population Safety and efficacy have not been established. ", "Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of melphalan injection in the elderly However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution in patients receiving this medicine. ", "There are no adequate studies in women for determining infant risk when using this medication during breastfeeding Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.", "Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur In these cases, your doctor may want to change the dose, or other precautions may be necessary When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.", "Using this medicine with any of the following medicines is not recommended Your doctor may decide not to treat you with this medication or change some of the other medicines you take.", "Measles Virus Vaccine, Live\\\\nMumps Virus Vaccine, Live\\\\nRotavirus Vaccine, Live\\\\nRubella Virus Vaccine, Live\\\\nVaricella Virus Vaccine, Live\\\\nZoster Vaccine, Live", "Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.", "Abciximab\\\\nAceclofenac\\\\nAcemetacin\\\\nAdenovirus Vaccine\\\\nAlfuzosin\\\\nAmlodipine\\\\nAmtolmetin Guacil\\\\nAnagrelide\\\\nApixaban\\\\nAranidipine\\\\nAspirin\\\\nBacillus of Calmette and Guerin Vaccine, Live\\\\nBenazepril\\\\nBepridil\\\\nBromfenac\\\\nBufexamac\\\\nBunazosin\\\\nCaptopril\\\\nCelecoxib\\\\nCholera Vaccine, Live\\\\nCholine Salicylate\\\\nCilnidipine\\\\nCilostazol\\\\nClevidipine\\\\nClonixin\\\\nClopidogrel\\\\nDabigatran Etexilate\\\\nDapiprazole\\\\nDengue Tetravalent Vaccine, Live\\\\nDexibuprofen\\\\nDexketoprofen\\\\nDiclofenac\\\\nDiflunisal\\\\nDiltiazem\\\\nDipyridamole\\\\nDipyrone\\\\nDoxazosin\\\\nDroxicam\\\\nEdoxaban\\\\nEnalapril\\\\nEnalaprilat\\\\nEptifibatide\\\\nEtodolac\\\\nEtofenamate\\\\nEtoricoxib\\\\nFelbinac\\\\nFelodipine\\\\nFenoprofen\\\\nFepradinol\\\\nFeprazone\\\\nFloctafenine\\\\nFlufenamic Acid\\\\nFlurbiprofen\\\\nFosinopril\\\\nIbuprofen\\\\nIndomethacin\\\\nInfluenza Virus Vaccine, Live\\\\nIsradipine\\\\nKetoprofen\\\\nKetorolac\\\\nLercanidipine\\\\nLisinopril\\\\nLornoxicam\\\\nLoxoprofen\\\\nLumiracoxib\\\\nManidipine\\\\nMeclofenamate\\\\nMefenamic Acid\\\\nMeloxicam\\\\nMoexipril\\\\nMorniflumate\\\\nMoxisylyte\\\\nNabumetone\\\\nNaproxen\\\\nNepafenac\\\\nNicardipine\\\\nNifedipine\\\\nNiflumic Acid\\\\nNimesulide\\\\nNimesulide Beta Cyclodextrin\\\\nNimodipine\\\\nNisoldipine\\\\nNitrendipine\\\\nOxaprozin\\\\nOxyphenbutazone\\\\nParecoxib\\\\nPerindopril\\\\nPhenoxybenzamine\\\\nPhentolamine\\\\nPhenylbutazone\\\\nPiketoprofen\\\\nPiroxicam\\\\nPoliovirus Vaccine, Live\\\\nPranoprofen\\\\nPrasugrel\\\\nPrazosin\\\\nProglumetacin\\\\nPropyphenazone\\\\nProquazone\\\\nQuinapril\\\\nRamipril\\\\nRivaroxaban\\\\nRofecoxib\\\\nSalicylic Acid\\\\nSalsalate\\\\nSilodosin\\\\nSmallpox Vaccine\\\\nSodium Salicylate\\\\nSulfinpyrazone\\\\nSulindac\\\\nTamsulosin\\\\nTenoxicam\\\\nTerazosin\\\\nTiaprofenic Acid\\\\nTicagrelor\\\\nTiclopidine\\\\nTirofiban\\\\nTolfenamic Acid\\\\nTolmetin\\\\nTrandolapril\\\\nTreprostinil\\\\nTrimazosin\\\\nTyphoid Vaccine, Live\\\\nUrapidil\\\\nValdecoxib\\\\nVerapamil\\\\nVorapaxar\\\\nWarfarin\\\\nYellow Fever Vaccine", "Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.", "Buthionine Sulfoximine\\\\nNalidixic Acid", "Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur Using alcohol or tobacco with certain medicines may also cause interactions to occur Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.", "The presence of other medical problems may affect the use of this medicine Make sure you tell your doctor if you have any other medical problems, especially:", "Allergy to heparin, history of or\\\\nAllergy to iodinated contrast agents not controlled by allergy medicine or steroids, history of or\\\\nAllergy to latex, history of or\\\\nAngina (chest pain) or\\\\nBleeding problems or\\\\nBlood clotting problems (eg, uncorrectable coagulopathy) or\\\\nBrain cancer, active or\\\\nHeart attack or\\\\nHeart disease or\\\\nHeart failure, new or worsening or\\\\nHeart rhythm problems or\\\\nLiver failure or\\\\nLiver treatment or surgery within the past 4 weeks or\\\\nPortal hypertension (high blood pressure in the liver portal vein) or\\\\nThrombocytopenia (low number of platelets), heparin-induced\\\\u2014Should not be used in patients with these conditions. ", "Anemia or\\\\nBone marrow suppression or\\\\nLeukopenia (low white blood cells) or\\\\nLiver disease or\\\\nThrombocytopenia (low platelets in the blood)\\\\u2014Use with caution May make these conditions worse. ", "Infection\\\\u2014May decrease your ability to fight an infection. ", "Kidney disease\\\\u2014Use with caution The effects may be increased because of slower removal of the medicine from the body. "]